A Case of Primary Cutaneous Histoplasmosis in a Patient with Diabetes and Multi‐Infarct Dementia
A Case of Primary Cutaneous Histoplasmosis in a Patient with Diabetes and Multi‐Infarct Dementia
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糖尿病合并多发梗死性痴呆患者原发性皮肤组织胞浆菌病一例
DOI：
10.1111/j.1346-8138.2002.tb00226.x
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
A. Lorincz
中科院分区：
文献类型：
--
作者：
A. Krunic;H. Carag;M. Medenica;A. Lorincz
我们报告一位50岁的非裔美国女性患有糖尿病和多发性梗死性痴呆症的原发性皮肤组织胞浆菌病。患者在额头意外的浅表创伤后出现发烧和结节溃烂的皮肤损害。活检显示化脓性肉芽肿性炎症，细胞内和细胞外有酵母菌样细胞，伴随3-4μm大小的透明晕。未发现全身受累。用伊曲康唑200 mg，每日2次，连续治疗3周后皮损消失。连续用药3个月，随访1年未见复发迹象。
We report a case of primary cutaneous histoplasmosis in a fifty‐year‐old African‐American woman with diabetes and multi‐infarct dementia. The patient developed fever and crusted, nodulo‐ulcerative lesions of the skin after accidental superficial trauma to the forehead. The biopsy revealed suppurative granulomatous inflammation with intracellular and extracellular yeast‐like cells with associated clear halo measuring 3–4 μm in size. Systemic involvement was not found. The lesions cleared after treatment with itraconazole 200 mg twice a day for 3 weeks. The medication was continued for a total period of 3 months, with no signs of recurrence after one‐year of follow‐up.
唑类在抗真菌治疗中的作用。
DOI：
10.1093/clinids/22.supplement_2.s148
发表时间：
1996
期刊：
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子：
--
作者：
Kauffman,CA
通讯作者：
Kauffman,CA