Use of a novel technology to track adherence to product use in a microbicide trial of short duration (MTN-007).
Use of a novel technology to track adherence to product use in a microbicide trial of short duration (MTN-007).
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DOI：
10.1007/s10461-013-0549-2
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发表时间：
2013-11
影响因子：
4.4
通讯作者：
McGowan, Ian
中科院分区：
文献类型：
--
作者：
Leu, Cheng-Shiun;Mabragana, Marina;Giguere, Rebecca;Dolezal, Curtis;Carballo-Dieguez, Alex;McGowan, Ian
杀菌剂试验中的依从性测量具有挑战性。为了减少回忆和社会期望偏差，我们在直肠杀菌剂试验中使用了交互式语音应答系统 (IVR)。四十六名参与者被要求报告一周内每天的产品使用情况。参与者每次通话都会获得奖励，并且每天通话还会获得奖金。我们检查了呼叫 IVR 和凝胶使用的遵守情况；我们将后者与涂抹器数量进行了比较。每天拨打 IVR 的依从性很高（平均值 = 89.9%，标准差 = 20.7%）。每次 IVR 凝胶使用的依从性非常好（平均值 = 90.7%，标准差 = 19.1%），并且 80.4% 的病例与涂抹器计数一致。坚持呼叫或使用凝胶均与时间因素（例如呼叫开始日、自第一次呼叫以来的天数或工作日与周末）相关。每日报告可以识别不正常的产品使用情况。 IVR 对于简短试验中的日常报告似乎很有用。
Adherence measurement in microbicide trials is challenging. To decrease recall and social desirability bias, we used an Interactive Voice Response system (IVR) in a rectal microbicide trial. Forty-six participants were asked to report product use daily for one week. Participants received an incentive per call plus a bonus for calling every day. We examined adherence to calling the IVR and to gel use; we compared the latter to applicator counts. Adherence to calling the IVR daily was high (mean=89.9%, sd=20.7%). Adherence to gel use per IVR was very good (mean=90.7%, sd=19.1%), and consistent with applicator counts in 80.4% of cases. Neither adherence to calling nor gel use were associated with temporal factors like day calls started, number of days since first call, or weekday vs. weekend. Daily reporting allowed identification of irregular product use. IVR appears useful for daily reporting in brief trials.
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影响因子：
3.7
作者：
McGowan I;Hoesley C;Cranston RD;Andrew P;Janocko L;Dai JY;Carballo-Dieguez A;Ayudhya RK;Piper J;Hladik F;Mayer K
通讯作者：
Mayer K
影响因子：
4.4
作者：
Haberer, Jessica E.;Robbins, Gregory K.;Ybarra, Michele;Monk, Alexandra;Ragland, Kathleen;Weiser, Sheri D.;Johnson, Mallory O.;Bangsberg, David R.
通讯作者：
Bangsberg, David R.
DOI：
10.1097/qai.0b013e31826f9962
发表时间：
2012-12-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Muchomba FM;Gearing RE;Simoni JM;El-Bassel N
通讯作者：
El-Bassel N
影响因子：
4.6
作者：
Schroder, Kerstin E E;Johnson, Christopher J
通讯作者：
Johnson, Christopher J
影响因子：
3.7
作者：
Pool, Robert;Montgomery, Catherine M.;McCormack, Sheena
通讯作者：
McCormack, Sheena