Clinical Aspects of Gut Microbiota in Hepatocellular Carcinoma Management.
Clinical Aspects of Gut Microbiota in Hepatocellular Carcinoma Management.
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DOI：
10.3390/pathogens10070782
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发表时间：
2021-06-22
期刊：
影响因子：
--
通讯作者：
Zeng Z
中科院分区：
文献类型：
--
作者：
Xu J;Zhan Q;Fan Y;Lo EKK;Zhang F;Yu Y;El-Nezami H;Zeng Z
Liver cancer, predominantly hepatocellular carcinoma (HCC), is the third leading cause of cancer-related deaths worldwide. Emerging data highlight the importance of gut homeostasis in the pathogenesis of HCC. Clinical and translational studies revealed the patterns of dysbiosis in HCC patients and their potential role for HCC diagnosis. Research on underlying mechanisms of dysbiosis in HCC development pointed out the direction for improving the treatment and prevention. Despite missing clinical studies, animal models showed that modulation of the gut microbiota by probiotics may become a new way to treat or prevent HCC development.
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25.7
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