Chronobiology of Exercise: Evaluating the Best Time to Exercise for Greater Cardiovascular and Metabolic Benefits.

Chronobiology of Exercise: Evaluating the Best Time to Exercise for Greater Cardiovascular and Metabolic Benefits.
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DOI:
10.1002/cphy.c210036
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发表时间:
2022-06-29
影响因子:
5.8
通讯作者:
Thosar, Saurabh S.
Thosar, Saurabh S.
中科院分区:
医学1区
文献类型:
--
作者:
Brito, Leandro C.;Marin, Thais C.;Azevedo, Luan;Rosa-Silva, Julia M.;Shea, Steven A.;Thosar, Saurabh S.

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生理功能在24小时内波动,这是由于持续的日常行为模式和环境变化,包括睡眠/清醒、休息/活动、光明/黑暗和每日温度循环。体内昼夜节律系统使身体为这些预期的行为和环境变化做好准备,帮助协调对这些日常变化的最佳心血管和代谢反应。此外,主要由夜间暴露在人造光下(例如,夜班工作时发生的)造成的昼夜节律紊乱,增加了心血管和新陈代谢发病率和死亡率的风险。定期锻炼是对抗心血管和代谢风险的一种对策,最近的研究结果表明,与早间锻炼相比,晚间锻炼对血压和自主神经控制的心血管益处更大。此外,运动还可以重置昼夜节律系统的时间,这增加了适当的运动时序被用来抵消昼夜节律干扰的可能性。这篇文章介绍了人体昼夜节律系统的整体功能相关性,并提供了围绕运动时间可以调节心血管和代谢益处的概念的证据。需要进一步的工作来建立锻炼作为一种工具,在昼夜节律失调后适当地重置昼夜节律系统,以保护心血管和代谢健康。
Physiological function fluctuates across 24 h due to ongoing daily patterns of behaviors and environmental changes, including the sleep/wake, rest/activity, light/dark, and daily temperature cycles. The internal circadian system prepares the body for these anticipated behavioral and environmental changes, helping to orchestrate optimal cardiovascular and metabolic responses to these daily changes. In addition, circadian disruption, caused principally by exposure to artificial light at night (e.g., as occurs with night-shift work), increases the risk for both cardiovascular and metabolic morbidity and mortality. Regular exercise is a countermeasure against cardiovascular and metabolic risk, and recent findings suggest that the cardiovascular benefits on blood pressure and autonomic control are greater with evening exercise compared to morning exercise. Moreover, exercise can also reset the timing of the circadian system, which raises the possibility that appropriate timing of exercise could be used to counteract circadian disruption. This article introduces the overall functional relevance of the human circadian system and presents the evidence surrounding the concepts that the time of day that exercise is performed can modulate the cardiovascular and metabolic benefits. Further work is needed to establish exercise as a tool to appropriately reset the circadian system following circadian misalignment to preserve cardiovascular and metabolic health.
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