Differentiating neural systems mediating the acquisition vs. expression of goal-directed and habitual behavioral control.
Differentiating neural systems mediating the acquisition vs. expression of goal-directed and habitual behavioral control.
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DOI：
10.1111/ejn.12897
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发表时间：
2015-05
期刊：
影响因子：
--
通讯作者：
O'Doherty JP
中科院分区：
文献类型：
--
作者：
Liljeholm M;Dunne S;O'Doherty JP
相当多的行为数据表明，操作性的行动可以成为习惯，证明了在行动结果的偶然性和主观结果值的变化不敏感。值得注意的是，尽管有几项研究调查了习惯的神经基础，但没有一项研究明确区分了人类大脑中支持习惯形成的区域和实施习惯控制的区域。我们用功能磁共振成像扫描参与者，因为他们学习和执行一项操作性任务，在该任务中，环境的条件结构鼓励对行为后果进行目标导向编码，或将行为映射到先行线索的习惯。在随后的评估结果贬值的不敏感性期间，参与者也被扫描。我们确定了小脑和腹侧纹状体在学习和测试表现中对结果贬值的行为不敏感性的可分离作用。我们还表明，顶叶下小叶-一个区域以前牵连在几个方面的目标导向的行动选择，包括归因的意图和意识的机构-预测结果贬值的敏感性。最后，我们揭示了一个潜在的功能之间的同源性，人类的膝下皮层和啮齿动物的边缘下皮层在执行习惯性控制。总之，我们的研究结果表明，一个广泛的系统划分，在皮层和皮层下水平，大脑区域之间的调解编码和表达的行动结果和刺激反应协会。
Considerable behavioral data indicates that operant actions can become habitual, as evidenced by insensitivity to changes in the action-outcome contingency and in subjective outcome values. Notably, although several studies have investigated the neural substrates of habits, none has clearly differentiated the areas of the human brain that support habit formation from those that implement habitual control. We scanned participants with fMRI as they learned and performed an operant task in which the conditional structure of the environment encouraged either goal-directed encoding of the consequences of actions, or a habit-like mapping of actions to antecedent cues. Participants were also scanned during a subsequent assessment of insensitivity to outcome devaluation. We identified dissociable roles of the cerebellum and ventral striatum, across learning and test performance, in behavioral insensitivity to outcome devaluation. We also show that the inferior parietal lobule – an area previously implicated in several aspects of goal-directed action selection, including the attribution of intent and awareness of agency – predicts sensitivity to outcome devaluation. Finally, we reveal a potential functional homology between the human subgenual cortex and rodent infralimbic cortex in the implementation of habitual control. In summary, our findings suggest a broad systems division, at the cortical and subcortical levels, between brain areas mediating the encoding and expression of action-outcome and stimulus-response associations.
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DOI：
10.1196/annals.1390.006
发表时间：
2007-01-01
期刊：
REWARD AND DECISION MAKING IN CORTICOBASAL GANGLIA NETWORKS
影响因子：
--
作者：
Balleine, Bernard W.;Ostlund, Sean B.
通讯作者：
Ostlund, Sean B.
DOI：
10.1080/14640748108400816
发表时间：
1981-01-01
期刊：
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY SECTION B-COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY
影响因子：
--
作者：
ADAMS, CD;DICKINSON, A
通讯作者：
DICKINSON, A
DOI：
10.1080/14640748308400912
发表时间：
1983-01-01
期刊：
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY SECTION B-COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY
影响因子：
--
作者：
DICKINSON, A;NICHOLAS, DJ;ADAMS, CD
通讯作者：
ADAMS, CD
影响因子：
3.3
作者：
Drevets, Wayne C.;Savitz, Jonathan
通讯作者：
Savitz, Jonathan
影响因子：
5.3
作者：
de Wit, Sanne;Watson, Poppy;Ridderinkhof, K. Richard
通讯作者：
Ridderinkhof, K. Richard