Hierarchically Structured Materials for Bone Regeneration: Biomimetic Morphology, Micro-Mechanics and Properties

Hierarchically Structured Materials for Bone Regeneration: Biomimetic Morphology, Micro-Mechanics and Properties
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用于骨再生的分层结构材料:仿生形态、微观力学和性能

DOI:
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发表时间:
2012
期刊:
影响因子:
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通讯作者:
Jörg Brandt
Jörg Brandt
中科院分区:
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文献类型:
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作者:
S. Henning;H. R. I. Khasim;G. Michler;Jörg Brandt

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该贡献描述了一种生物相容性纳米复合材料的开发,该材料由可吸收聚合物基质和骨诱导纳米颗粒组成,可用于制造致密产品、多孔支架、混合纳米纤维和交替多孔/致密结构。结果表明,该材料具有良好的刚度、强度和韧性平衡。该材料支持成骨细胞增殖。基于模块化设计原则,提出了几个原型分层三维结构。
The contribution describes the development of a biocompatible nanocomposite material consisting of a resorbable polymeric matrix and osteoinductive nanoparticles that can be used to manufacture compact products, porous scaffolds, hybrid nanofibers, and alternating porous/compact structures. It is shown that the material has a good balance of stiffness, strength and toughness. The material supports osteoblast proliferation. Based on a modular design principle, several prototypes for hierarchical 3D constructs are proposed.
DOI: 10.1016/s0021-9290(99)00111-6
发表时间: 1999-10-01
影响因子: 2.4
作者:
Zysset, PK;Guo, XE;Goldstein, SA
通讯作者: Goldstein, SA