Neurons in primary auditory cortex represent sound source location in a cue-invariant manner

Neurons in primary auditory cortex represent sound source location in a cue-invariant manner
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初级听觉皮层中的神经元以线索不变的方式表示声源位置

DOI:
10.1038/s41467-019-10868-9
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发表时间:
2019
影响因子:
16.6
通讯作者:
J. Bizley
J. Bizley
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Katherine C. Wood;S. M. Town;J. Bizley

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听觉皮层是声音定位所必需的,但听觉皮层中的神经放电如何构成我们对空间声源感知的基础仍不清楚。具体来说,听觉皮层中的神经元是否代表空间线索或跨线索的听觉空间的综合表示尚不清楚。在这里,我们测量了雪貂执行相对定位任务时初级听觉皮层(A1)神经元的空间感受野。操纵双耳和频谱定位线索的可用性对雪貂的表现或神经空间调谐几乎没有影响。一个亚群的神经元编码的空间位置一致的本地化线索类型。此外,神经放电模式解码器优于使用群体活动的双通道模型解码器。总之,这些观察结果表明,A1编码声源的位置,而不是空间线索值。大脑的听觉皮层不仅参与声音的检测,还参与定位声音。在这里,作者表明,雪貂初级听觉皮层(A1)的神经元编码声源的位置,而不仅仅是反映空间线索。
Auditory cortex is required for sound localisation, but how neural firing in auditory cortex underlies our perception of sound sources in space remains unclear. Specifically, whether neurons in auditory cortex represent spatial cues or an integrated representation of auditory space across cues is not known. Here, we measured the spatial receptive fields of neurons in primary auditory cortex (A1) while ferrets performed a relative localisation task. Manipulating the availability of binaural and spectral localisation cues had little impact on ferrets’ performance, or on neural spatial tuning. A subpopulation of neurons encoded spatial position consistently across localisation cue type. Furthermore, neural firing pattern decoders outperformed two-channel model decoders using population activity. Together, these observations suggest that A1 encodes the location of sound sources, as opposed to spatial cue values. The brain's auditory cortex is involved not just in detection of sounds, but also in localizing them. Here, the authors show that neurons in ferret primary auditory cortex (A1) encode the location of sound sources, as opposed to merely reflecting spatial cues.
DOI: 10.1152/jn.00392.2006
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T. M. Woods;Steve E. Lopez;James H. Long;Joanne E. Rahman;G. Recanzone
通讯作者: T. M. Woods;Steve E. Lopez;James H. Long;Joanne E. Rahman;G. Recanzone
猕猴听觉皮层在声音定位中的作用。
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发表时间: 1997
期刊: Acta oto-laryngologica. Supplementum
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