The effect of posttraumatic stress disorder on risk-taking propensity among crack/cocaine users in residential substance abuse treatment.

The effect of posttraumatic stress disorder on risk-taking propensity among crack/cocaine users in residential substance abuse treatment.
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DOI:
10.1002/da.20637
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发表时间:
2009
影响因子:
7.4
通讯作者:
Lejuez, C. W.
Lejuez, C. W.
中科院分区:
医学1区
文献类型:
--
作者:
Tull, Matthew T.;Trotman, Adria;Duplinsky, Michelle S.;Reynolds, Elizabeth K.;Daughters, Stacey B.;Potenza, Marc N.;Lejuez, C. W.

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研究发现,创伤后应激障碍 (PTSD) 和物质使用障碍 (SUD) 的同时发生与一系列负面临床结果(例如复发、自杀、法律问题、艾滋病毒感染)有关。然而,对于可能使同时患有 PTSD 和 SUD 诊断的个体面临这些结果风险的特定因素知之甚少。冒险倾向的构建可能具有特殊的前景。为了调查冒险倾向与 PTSD-SUD 患者的相关性,我们对 90 名接受住院药物滥用治疗的快克/可卡因依赖患者(n = 20)或没有(n = 70)当前 PTSD 诊断的冒险倾向差异进行了检查。使用既定的基于行为的测量方法——气球模拟风险任务(BART)来评估冒险倾向。患有 PTSD 的快克/可卡因依赖患者比没有 PTSD 的患者表现出明显更高水平的冒险倾向,即使在控制共病精神疾病和当前精神药物使用的情况下,这种差异仍然显着。没有发现证据表明从任务开始到结束冒险倾向的变化模式与 PTSD 状态有关。尽管是初步结果,但结果表明需要进一步调查冒险倾向,将其作为可能与患有 PTSD 的快克/可卡因使用者中观察到的负面临床结果相关的一个因素。
The co-occurrence of posttraumatic stress disorder (PTSD) and substance use disorders (SUDs) has been found to be associated with a range of negative clinical outcomes (e.g., relapse, suicide, legal problems, HIV infection). However, less is known about the particular factors that may be placing individuals with a co-occurring PTSD and SUD diagnosis at risk for these outcomes. The construct of risk-taking propensity may hold particular promise. To investigate the relevance of risk-taking propensity to PTSD-SUD patients, differences in risk-taking propensity were examined among 90 crack/cocaine dependent patients in residential substance abuse treatment with (n = 20) or without (n = 70) a current PTSD diagnosis. Risk-taking propensity was assessed using an established behaviorally-based measure, the Balloon Analogue Risk Task (BART). Crack/cocaine dependent patients with PTSD exhibited significantly greater levels of risk-taking propensity than patients without PTSD, and this difference remained significant even when controlling for the presence of comorbid psychiatric disorders and current psychotropic medication use. No evidence was found for a different pattern of change in risk-taking propensity from the beginning to the end of the task as a function of PTSD status. Although preliminary, results suggest the need to further investigate risk-taking propensity as a factor that may be associated with the negative clinical outcomes observed among crack/cocaine users with PTSD.
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