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Proteoglycan 4 (PRG4) characterization and supplementation in human post-knee injury synovial fluid: Implications for restoration of impaired cartilage lubricating ability and osteoarthritis biotherapeutics

Proteoglycan 4 (PRG4) characterization and supplementation in human post-knee injury synovial fluid: Implications for restoration of impaired cartilage lubricating ability and osteoarthritis biotherapeutics
人膝损伤后滑液中蛋白聚糖 4 (PRG4) 的表征和补充:对恢复受损软骨润滑能力和骨关节炎生物治疗的影响
批准号:
199721
负责人:
Hill Taryn
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-02-01 至 2011-02-01

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英文摘要
Proteoglycan 4 (PRG4) proteins are produced by the cells within articular joints and are present in the synovial fluid (SF) of joints. PRG4 contributes to the lubrication of articular cartilage, preventing wear and degradation of the cartilage. Decrease
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