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The role of human glyceraldehyde-3-phosphate dehydrogenase in reactivating oxidized forms of the DNA repair enzyme APE1

The role of human glyceraldehyde-3-phosphate dehydrogenase in reactivating oxidized forms of the DNA repair enzyme APE1
人甘油醛-3-磷酸脱氢酶在重新激活氧化形式的 DNA 修复酶 APE1 中的作用
批准号：
171666
负责人：
Ramotar Dindial
金额：
$25.88万
依托单位：
CIUSSS Est-de-l'Ile-de- Montral-Maisonneuve Rosemont
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2008
资助国家：
加拿大
项目状态：
已结题
起止时间：
2008-09-01 至 2011-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=171666&lang=en
关键词：
Cell Biology Dna Repair Neurological Diseases Oxidative Dna Damage Oxidized Proteins Protein-Protein Interactions

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Project summary: Reactive oxygen species are highly unstable molecules and are produced, e.g., by mitochondrial respiration and activated neutrophils. These reactive oxygen species can attack and destroy various cellular macromolecules such as proteins or
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The role of human glyceraldehyde-3-phosphate dehydrogenase in maintaining the redox state of the DNA repair enzyme APE1
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