Effects of S1P receptor directed pharmaceutical agents on central nervous system myelination
S1P受体定向药物对中枢神经系统髓鞘形成的影响
基本信息
- 批准号:221592
- 负责人:
- 金额:$ 12.98万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2010
- 资助国家:加拿大
- 起止时间:2010-09-01 至 2013-09-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The neurologic disorder multiple sclerosis (MS) involves injury and destruction of the myelin membrane that ensheaths nerve fibers (axons) and is required for efficient electrical conduction with the central nervous system (CNS). We postulate that the ove
神经系统疾病多发性硬化症(MS)涉及包裹神经纤维(轴突)的髓鞘膜的损伤和破坏,这是与中枢神经系统(CNS)进行有效电传导所必需的。我们假设爱河
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Antel Jack P其他文献
Antel Jack P的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
相似海外基金
Elucidation of the novel mechanism of multiple sclerosis based on the molecular mimicry between gut microbial and myelin antigens
基于肠道微生物和髓磷脂抗原之间的分子模拟阐明多发性硬化症的新机制
- 批准号:
23K14765 - 财政年份:2023
- 资助金额:
$ 12.98万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Longitudinal Assessment of Cognitive Impairment in Multiple Sclerosis with Advanced Brain Magnetic Resonance Imaging Measures of Myelin
采用先进的髓鞘质脑磁共振成像技术对多发性硬化症认知障碍进行纵向评估
- 批准号:
486297 - 财政年份:2022
- 资助金额:
$ 12.98万 - 项目类别:
Studentship Programs
Promoting remyelination in multiple sclerosis by simultaneously modulating myelin debris clearance and myelin lipid synthesis
通过同时调节髓磷脂碎片清除和髓磷脂脂质合成促进多发性硬化症的髓鞘再生
- 批准号:
10621894 - 财政年份:2022
- 资助金额:
$ 12.98万 - 项目类别:
Improving the Assessment of Myelin and Axonal Integrity in Early Multiple Sclerosis
改善早期多发性硬化症髓磷脂和轴突完整性的评估
- 批准号:
10426053 - 财政年份:2021
- 资助金额:
$ 12.98万 - 项目类别:
Demonstrating proof of concept of a first-in-class metabolic reprogramming agent that aims to promote myelin regeneration and anti-inflammatory effects in patients with Multiple Sclerosis
展示一流的代谢重编程剂的概念证明,旨在促进多发性硬化症患者的髓磷脂再生和抗炎作用
- 批准号:
81511 - 财政年份:2021
- 资助金额:
$ 12.98万 - 项目类别:
Collaborative R&D
Improving the Assessment of Myelin and Axonal Integrity in Early Multiple Sclerosis
改善早期多发性硬化症髓磷脂和轴突完整性的评估
- 批准号:
10662233 - 财政年份:2021
- 资助金额:
$ 12.98万 - 项目类别:
Prediction of Cognitive and Motor Symptom Progression in Multiple Sclerosis Using Myelin Imaging
使用髓磷脂成像预测多发性硬化症的认知和运动症状进展
- 批准号:
444954 - 财政年份:2021
- 资助金额:
$ 12.98万 - 项目类别:
Operating Grants
Spatiotemporal tuning of myelin antigens and rapamycin for enhanced antigen-specific immune tolerance in multiple sclerosis.
髓磷脂抗原和雷帕霉素的时空调节可增强多发性硬化症的抗原特异性免疫耐受。
- 批准号:
10325547 - 财政年份:2021
- 资助金额:
$ 12.98万 - 项目类别:
Longitudinal Neurocognitive Outcomes and Trajectories of Brain Development in Pediatric Patients with Multiple Sclerosis and Relapsing Myelin Oligodendrocyte Glycoprotein (MOG) Disease
多发性硬化症和复发性髓磷脂少突胶质细胞糖蛋白 (MOG) 病儿科患者的纵向神经认知结果和大脑发育轨迹
- 批准号:
416816 - 财政年份:2019
- 资助金额:
$ 12.98万 - 项目类别:
Studentship Programs
Imaging analysis of myelin pathologies in multiple sclerosis using q-Space Myelin Map method
使用 q 空间髓磷脂图方法对多发性硬化症的髓磷脂病理进行影像分析
- 批准号:
18K07508 - 财政年份:2018
- 资助金额:
$ 12.98万 - 项目类别:
Grant-in-Aid for Scientific Research (C)