Molecular characterization and inhibition of the PCSK9-assisted low-density lipoprotein receptor degradation pathway.
Molecular characterization and inhibition of the PCSK9-assisted low-density lipoprotein receptor degradation pathway.
PCSK9 辅助低密度脂蛋白受体降解途径的分子表征和抑制。
批准号：
215523
负责人：
Mayer Gatan
金额：
$7.29万
依托单位：
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-09-01 至 2011-09-01
中文摘要
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英文摘要
Atherosclerosis is a progressive disease in which fatty deposits build up within the arteries and interfere with the vital blood supply to body organs. It is at the origin of the majority of heart attacks and strokes that are the main cause of death world
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Preclinical development of highly potent and orally bioavailable PCSK9 inhibitors for patients at high cardiovascular risk
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批准号：494266
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项目类别：Operating Grants
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资助金额：$7.29万
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财政年份：2023
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负责人：Mayer Gatan
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依托单位：
Function of PCSK9 in LDLR and CD36 degradation: LDL cholesterol regulation and beyond.
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批准号：293225
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项目类别：Operating Grants
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资助金额：$38.21万
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财政年份：2013
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负责人：Mayer Gatan
-
依托单位：
The PCSK9-induced degradation of cell surface receptors: LDL cholesterol regulation and beyond.
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批准号：274738
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项目类别：Operating Grants
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资助金额：$7.29万
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财政年份：2012
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负责人：Mayer Gatan
-
依托单位：
Molecular characterization and inhibition of the PCSK9-assisted low-density lipoprotein receptor degradation pathway.
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批准号：231136
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项目类别：Operating Grants
-
资助金额：$7.29万
-
财政年份：2011
-
负责人：Mayer Gatan
-
依托单位：
海外基金