Role of the PINK1/Parkin mitochondrial quality control pathway in dopaminergic neurons

PINK1/Parkin 线粒体质量控制通路在多巴胺能神经元中的作用

• 批准号: 226501
• 负责人: Burman Jonathon L
• 金额: $ 10.62万
• 依托单位: University of Washington (Seattle)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-02-01 至 2014-01-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=226501&lang=en
• 关键词: Aging; Biochemistry; Drosophila; Flow Cytometry; Genetics; Membranes; Mitochondria; Neurodegeneration; Neurons; Single Cell Analysis

Mitochondria are organelles with numerous cellular functions, including the production of the majority of cellular energy. Mitochondria contain their own genome, and mutations in this genome are linked to many prevalent diseases, including the neurodegene

线粒体是具有许多细胞功能的细胞器，包括产生大部分细胞能量。线粒体含有自己的基因组，该基因组中的突变与许多流行疾病有关，包括神经退行性疾病