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Evaluation of spleen tyrosine kinase as a potential therapeutic target in treatment of early B cell acute lymphoblastic leukemia

Evaluation of spleen tyrosine kinase as a potential therapeutic target in treatment of early B cell acute lymphoblastic leukemia
脾酪氨酸激酶作为早期 B 细胞急性淋巴细胞白血病潜在治疗靶点的评价
批准号：
184705
负责人：
Perova Tatiana
金额：
$7.65万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2008
资助国家：
加拿大
项目状态：
已结题
起止时间：
2008-10-01 至 2011-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=184705&lang=en
关键词：
Acute Lymphoblastic Leukemia B Cell Development Flow Cytometry Gene Expresssion Microarrays Mouse Models Pre-B Cell Receptor Signaling Pre-Clinical Testing Spleen Tyrosine Kinase Xenotransplantation

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英文摘要
Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer accounting for 25% of all cancer diagnosed in children. Over the past years, great progress have been made in the treatment of ALL; however, at least 25% of pediatric patients
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