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Strategies for gene discovery in schizophrenia: subphenotypes, deep sequencing, and interactions

Strategies for gene discovery in schizophrenia: subphenotypes, deep sequencing, and interactions
精神分裂症基因发现策略：亚表型、深度测序和相互作用
批准号：
226858
负责人：
Kennedy James L
金额：
$57.64万
依托单位：
Centre for Addiction and Mental Health (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-03-01 至 2016-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=226858&lang=en
关键词：
Association Endophenotypes Eye Tracking Facial Dysmorphology Gene Sequencing Gene-Environment Interactions Response Schizophrenia

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中文摘要
翻译
精神分裂症(SCZ)是一种主要的精神疾病，一生的患病率约为1%，加拿大医疗保健系统每年花费高达40亿美元。家族中出现SCZ提示独特的易感因素(基因
英文摘要
Schizophrenia (SCZ) is a major psychiatric disease that has a life-time prevalence of approximately 1%, and costs up to $4 billion dollars per year to the Canadian health care system. Occurrence of SCZ in family suggests unique vulnerability factors (gene
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Influence of polygenic risk scores on longitudinal disease trajectories of individuals with schizophrenia spectrum disorders
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