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Antiandrogenic and antiproliferative effects of diindolylmethane (DIM) and ring-substituted analogs (ring-DIMs) in androgen -ependent and -independent human prostate cancer cells in vitro, and in vivo using real-time imaging technology.

Antiandrogenic and antiproliferative effects of diindolylmethane (DIM) and ring-substituted analogs (ring-DIMs) in androgen -ependent and -independent human prostate cancer cells in vitro, and in vivo using real-time imaging technology.
使用实时成像技术，在体外和体内，二吲哚甲烷（DIM）和环取代类似物（环-DIM）对雄激素依赖性和非依赖性人前列腺癌细胞的抗雄激素和抗增殖作用。
批准号：
226074
负责人：
Sanderson J. Thomas
金额：
$25.18万
依托单位：
INRS-Institut Armand-Frappier (Laval)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-03-01 至 2014-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=226074&lang=en
关键词：
Androgen Dependent Androgen Independent Androgen Receptor Signaling Pathways Antiandrogens Apoptosis Diindolylmethane Derivatives Human Prostate In Vivo Imaging And Reduction Of Animal Use Lncap And Pc-3 Cell Culture Steroidogenesis And Enzyme Ki

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