Antiandrogenic and antiproliferative effects of diindolylmethane (DIM) and ring-substituted analogs (ring-DIMs) in androgen -ependent and -independent human prostate cancer cells in vitro, and in vivo using real-time imaging technology.

使用实时成像技术，在体外和体内，二吲哚甲烷（DIM）和环取代类似物（环-DIM）对雄激素依赖性和非依赖性人前列腺癌细胞的抗雄激素和抗增殖作用。

• 批准号: 226074
• 负责人: Sanderson J. Thomas
• 金额: $ 25.18万
• 依托单位: INRS-Institut Armand-Frappier (Laval)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-03-01 至 2014-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=226074&lang=en
• 关键词: Androgen Dependent; Androgen Independent; Androgen Receptor Signaling Pathways; Antiandrogens; Apoptosis; Diindolylmethane Derivatives; Human Prostate; In Vivo Imaging And Reduction Of Animal Use; Lncap And Pc-3 Cell Culture; Steroidogenesis And Enzyme Ki

Numerous studies have shown the protective effects against cancer of high vegetable consumption, particularly that of cruciferous vegetables of the Brassica family (broccoli, cauliflower, cabbage). These vegetables contain high amounts of the compound ind

许多研究表明，大量食用蔬菜，特别是十字花科蔬菜（花椰菜，花椰菜，卷心菜）对癌症有保护作用。这些蔬菜含有大量的复合维生素D，