课题基金 / 基金详情

Antiandrogenic and antiproliferative effects of diindolylmethane (DIM) and ring-substituted analogs (ring-DIMs) in LNCaP and PC-3 human prostate cancer cells in vitro, and in vivo using real-time imaging technology

Antiandrogenic and antiproliferative effects of diindolylmethane (DIM) and ring-substituted analogs (ring-DIMs) in LNCaP and PC-3 human prostate cancer cells in vitro, and in vivo using real-time imaging technology
使用实时成像技术在体外和体内的 LNCaP 和 PC-3 人前列腺癌细胞中二吲哚甲烷 (DIM) 和环取代类似物 (ring-DIM) 的抗雄激素和抗增殖作用
批准号：
176577
负责人：
Sanderson J. Thomas
金额：
$5.81万
依托单位：
INRS-Institut Armand-Frappier (Laval)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2008
资助国家：
加拿大
项目状态：
已结题
起止时间：
2008-09-01 至 2009-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=176577&lang=en
关键词：
Antiandrogens And Signaling Pathways Diindolylmethane And Derivatives Human Prostate In Vivo Imaging And Reduction Of Animal Use Lncap And Pc-3 Cell Culture Steroidogenesis And Enzyme Kinetic Analysis

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中文摘要
翻译
大量研究表明，大量食用蔬菜可以预防癌症，尤其是十字花科蔬菜(花椰菜、花椰菜、卷心菜)。这些蔬菜含有大量的吲哚-3-卡宾
英文摘要
Numerous studies have shown the protective effects against cancer of high vegetable consumption, particularly that of cruciferous vegetables of the Brassica family (broccoli, cauliflower, cabbage). These vegetables contain high amounts of indole-3-carbino
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