Engineering the next generation of scaffolds

设计下一代脚手架

• 批准号: LP160100988
• 负责人: A/Prof Vincent Gomes
• 金额: $ 29.86万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-06-15 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP160100988
• 关键词: Engineering; next; generation; scaffolds

Engineering the next generation of scaffolds. This project aims to develop high efficiency quantum dots based on carbon nanomaterials, integrated with scaffolds and viable tissue cells, which can be used to develop smart implants with monitoring capabilities to reduce patient trauma and expenses. In certain cases, more than 50% of medical implants fail. Improving effective intervention is urgently needed, particularly monitoring of implants and early diagnosis to prevent rejections and adverse reactions. Current methods are inefficient, expensive, and induce toxicity. A non-toxic and non-invasive method to monitor the progress of tissue regeneration and wound healing is expected to place Australia at the forefront of developing implants.

设计下一代支架。该项目旨在开发基于碳纳米材料的高效量子点，与支架和活组织细胞相结合，可用于开发具有监测能力的智能植入物，以减少患者创伤和费用。在某些情况下，超过50%的医疗植入物失败。迫切需要改善有效的干预措施，特别是监测植入物和早期诊断，以防止排斥反应和不良反应。目前的方法效率低，价格昂贵，并诱导毒性。一种监测组织再生和伤口愈合进展的无毒和非侵入性方法有望使澳大利亚处于开发植入物的最前沿。