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Role of the hypothalamo-pancreatic axis in the pathogenesis of type 2 diabetes

Role of the hypothalamo-pancreatic axis in the pathogenesis of type 2 diabetes
下丘脑-胰轴在2型糖尿病发病机制中的作用
批准号:
226247
负责人:
Alquier Thierry
金额:
$32.19万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-03-01 至 2015-03-01

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中文摘要
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英文摘要
Excessive consumption of nutrients with high caloric density and obesity negatively affect insulin action in peripheral and central insulin-sensitive tissues including muscle, liver and the central nervous system (CNS) which in turn promote type 2 diabete
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Central control of energy homeostasis by neuronal adipose triglyceride lipase
Gliopeptidic regulation of hypothalamic neuronal circuitry by endozepines and energy balance
Role of the hypothalamo-pancreatic axis in the pathogenesis of type 2 diabetes
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