Selective inhibition of Unfolded Protein Response-mediated XBP-1 splicing to prevent progression of inflammatory and fibrotic chronic lung disease
Selective inhibition of Unfolded Protein Response-mediated XBP-1 splicing to prevent progression of inflammatory and fibrotic chronic lung disease
选择性抑制未折叠蛋白反应介导的 XBP-1 剪接以预防炎症和纤维化慢性肺病的进展
批准号：
327891
负责人：
Ayaub Ehab
金额：
$7.65万
依托单位：
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-10-01 至 2017-10-01
中文摘要
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英文摘要
The molecular mechanisms that contribute to chronic tissue scarring and inflammation in the lung remain to be fully understood. Recent evidence has shown that mechanisms involved in protein homeostasis are associated with chronic fibrotic and inflammatory
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