Cellular mechanotransduction in the actin cytoskeleton

肌动蛋白细胞骨架中的细胞力转导

• 批准号: 340762
• 负责人: Ehrlicher Allen J
• 金额: $ 21.86万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Salary Programs
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-12-01 至 2020-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=340762&lang=en
• 关键词: Actin; Cell Forces; Cell Mechanics; Cytoskeleton; Elasticity; Filamin; Mechanobiology; Mechanotransduction; Motility; Traction Force Microscopy

Cells are not only affected by chemical factors, but are also highly sensitive to forces. Mechanical stresses applied to cells change their behavior and activity; this conversion of force to biochemical response is referred to as "mechanotransduction", an

细胞不仅受化学因素影响，而且对力高度敏感。施加到细胞的机械应力改变它们的行为和活性;这种力到生化反应的转换被称为“机械转导”，