Testing the Role of Myb-like SWIRM and MPN domains 1 (MYSM1) Catalytic Activity in Transcriptional Regulation of Hematopoiesis

测试 Myb 样 SWIRM 和 MPN 结构域 1 (MYSM1) 催化活性在造血转录调节中的作用

• 批准号: 367225
• 负责人: Lin Yun Hsiao
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-12-01 至 2017-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=367225&lang=en
• 关键词: Hematopoiesis; Hematopoietic Stem Cells (Hscs); Lymphocyte Development; Molecular Genetics; Mouse Models; Myb-Like Swirm And Mpn Domains 1 (Mysm1); Mysm1-Deficiency Disorder; P53 Stress Response; Regulation Of Gene Expression

Introduction: All the cells of our blood and immune system are derived from rare hematopoietic stem cells (HSCs) in our bone marrow, through a process of cell proliferation and differentiation known as hematopoiesis. MYSM1 is a protein essential for the m

我们血液和免疫系统的所有细胞都来自骨髓中罕见的造血干细胞（hsc），通过一个称为造血的细胞增殖和分化过程。MYSM1是线粒体必需的一种蛋白质