Role of c-Myc in normal and leukemic human hematopoietic stem cells (HSCs)

c-Myc 在正常和白血病人类造血干细胞 (HSC) 中的作用

• 批准号: 311739
• 负责人: Bulaeva Elizaveta
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-12-01 至 2014-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=311739&lang=en
• 关键词: Bone Marrow; C-Myc Overexpression; Cellular Differentiation; Hematology; Human Hematopoietic Stem Cell; In Vitro Stem Cell Expansion; Lentiviral Transduction; Leukemia; Self-Renewal; Umbilical Cord Blood

Background: Current evidence indicates that both normal and leukemic human blood cell populations are sustained by very rare stem cells with unique phenotypes and proliferation control mechanisms. Interestingly, reproducible methods that support the prod

背景资料： 目前的证据表明，正常和白血病的人血细胞群体都是由非常罕见的干细胞维持的，具有独特的表型和增殖控制机制。有趣的是，可重复的方法，支持产品