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Comprehensive dissection of functional dependencies in a model protein network to reveal the mechanisms of robustness and fragility

Comprehensive dissection of functional dependencies in a model protein network to reveal the mechanisms of robustness and fragility
全面剖析模型蛋白质网络中的功能依赖性,揭示稳健性和脆弱性机制
批准号:
368536
负责人:
Landry Christian
金额:
$76.63万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

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中文摘要
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英文摘要
Every human is born with new mutations. Some of these mutations have devastating effects on newborns but most of these mutations have no effect on cell physiology, even if they slightly alter gene functions. This robustness to mutations is due to the arch
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Canada Research Chairs - Tier 1
  • 批准号:
    424785
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2019
  • 负责人:
    Landry Christian
  • 依托单位:
A foundation grant for bridging the mutation and interactome landscapes of the eukaryotic cell
  • 批准号:
    368010
  • 项目类别:
    Operating Grants
  • 资助金额:
    $155.95万
  • 财政年份:
    2017
  • 负责人:
    Landry Christian
  • 依托单位:
Genetic dissection of conserved cross talks among pathways involved in human diseases in a model system
  • 批准号:
    304138
  • 项目类别:
    Operating Grants
  • 资助金额:
    $49.23万
  • 财政年份:
    2014
  • 负责人:
    Landry Christian
  • 依托单位:
A comprehensive genotype-phenotype map of a eukaryotic complexome
  • 批准号:
    279305
  • 项目类别:
    Operating Grants
  • 资助金额:
    $46.26万
  • 财政年份:
    2013
  • 负责人:
    Landry Christian
  • 依托单位:
海外基金