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Engineering flagellin-specific Tregs to restore intestinal homeostasis in IBD

Engineering flagellin-specific Tregs to restore intestinal homeostasis in IBD
改造鞭毛蛋白特异性 Tregs 以恢复 IBD 肠道稳态
批准号：
376066
负责人：
Boardman Dominic
金额：
$9.83万
依托单位：
BC Children's Hospital Research Institute
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-11-01 至 2020-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=376066&lang=en
关键词：
Cell Therapy Chimeric Antigen Receptors Epitope Mapping Flow Cytometry Gene Transduction And Crispr/Cas9 Histology In Vivo Models Inflammatory Bowel Disease Regulatory T Cells T Cell/Treg Characterisation And Functional Assays

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中文摘要
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英文摘要
Inflammatory bowel disease (IBD) is a group of severe, incurable chronic conditions which affect approximately 1/150 Canadians. IBD results from uncontrolled inflammation in the gut, causing symptoms such as diarrhoea, abdominal pain, bleeding and weight
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