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Proteolytically derived peptide fragments of E-cadherin mediate epithelial restitution: a new paradigm for mucosal healing in inflammatory bowel diseases

Proteolytically derived peptide fragments of E-cadherin mediate epithelial restitution: a new paradigm for mucosal healing in inflammatory bowel diseases
E-钙粘蛋白的蛋白水解衍生肽片段介导上皮恢复:炎症性肠病粘膜愈合的新范例
批准号:
384147
负责人:
MacNaughton Wallace K
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-03-01 至 2019-03-01

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英文摘要
Gastroenterologists assess healing of the intestine, not just symptom relief, as the gold standard for determining the effectiveness of drug treatment of IBD. However, the biological mechanisms that regulate the healing process are complex and poorly und
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Banff Inflammation Workshop 2023
  • 批准号:
    467997
  • 项目类别:
    Miscellaneous Programs
  • 资助金额:
    $0.73万
  • 财政年份:
    2022
  • 负责人:
    MacNaughton Wallace K
  • 依托单位:
Protease-activated receptor (PAR)-2: A novel effector of mucosal healing in inflammatory bowel diseases
  • 批准号:
    354779
  • 项目类别:
    Operating Grants
  • 资助金额:
    $72.73万
  • 财政年份:
    2016
  • 负责人:
    MacNaughton Wallace K
  • 依托单位:
Banff Inflammation Workshop 2013
  • 批准号:
    264688
  • 项目类别:
    Miscellaneous Programs
  • 资助金额:
    $1.82万
  • 财政年份:
    2012
  • 负责人:
    MacNaughton Wallace K
  • 依托单位:
Regulation of intestinal epithelial permeability by serine proteases
  • 批准号:
    237182
  • 项目类别:
    Operating Grants
  • 资助金额:
    $41.72万
  • 财政年份:
    2011
  • 负责人:
    MacNaughton Wallace K
  • 依托单位:
海外基金