课题基金 / 基金详情

Approaches to regulate Cbl ubiquitin ligase activity and control oncogenic tyrosine kinase signaling.

Approaches to regulate Cbl ubiquitin ligase activity and control oncogenic tyrosine kinase signaling.
调节 Cbl 泛素连接酶活性和控制致癌酪氨酸激酶信号传导的方法。
批准号:
401834
负责人:
McGlade Catherine J
金额:
$66.04万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-03-01 至 2024-03-01

项目摘要

项目成果

McGlade Catherine J的其他基金

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中文摘要
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英文摘要
Leukemia is the most common cancer in children and adolescents, accounting for about one out of three cancers in children. Recently, a protein Cbl has been found to have mutations in childhood leukemia. These mutations prevent Cbl from performing its fun
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Alternative splicing and Numb protein isoform function in cancer metastasis.
  • 批准号:
    451565
  • 项目类别:
    Operating Grants
  • 资助金额:
    $62.7万
  • 财政年份:
    2021
  • 负责人:
    McGlade Catherine J
  • 依托单位:
Identifying novel signaling pathways in BCR-ABL driven leukemia.
  • 批准号:
    366610
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2016
  • 负责人:
    McGlade Catherine J
  • 依托单位:
Function and regulation of Numb protein isoforms in cancer.
  • 批准号:
    321543
  • 项目类别:
    Operating Grants
  • 资助金额:
    $59.55万
  • 财政年份:
    2015
  • 负责人:
    McGlade Catherine J
  • 依托单位:
Function and regulation of Numb alternative splicing in cancer.
  • 批准号:
    200602
  • 项目类别:
    Operating Grants
  • 资助金额:
    $47.66万
  • 财政年份:
    2010
  • 负责人:
    McGlade Catherine J
  • 依托单位: