Approaches to regulate Cbl ubiquitin ligase activity and control oncogenic tyrosine kinase signaling.
Approaches to regulate Cbl ubiquitin ligase activity and control oncogenic tyrosine kinase signaling.
批准号:
401834
负责人:
McGlade Catherine J
金额:
$66.04万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-03-01 至 2024-03-01
中文摘要
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英文摘要
Leukemia is the most common cancer in children and adolescents, accounting for about one out of three cancers in children. Recently, a protein Cbl has been found to have mutations in childhood leukemia. These mutations prevent Cbl from performing its fun
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