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Alternative splicing and Numb protein isoform function in cancer metastasis.

Alternative splicing and Numb protein isoform function in cancer metastasis.
选择性剪接和 Numb 蛋白亚型在癌症转移中发挥作用。
批准号:
451565
负责人:
McGlade Catherine J
金额:
$62.7万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01

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中文摘要
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英文摘要
In a normal cell, growth is regulated by signals that come from the surrounding tissue and neighboring cells. Signals from outside are interpreted by protein receptors that span the limiting membrane of the cell (half inside and half outside). A signal re
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Approaches to regulate Cbl ubiquitin ligase activity and control oncogenic tyrosine kinase signaling.
  • 批准号:
    401834
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.04万
  • 财政年份:
    2019
  • 负责人:
    McGlade Catherine J
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Identifying novel signaling pathways in BCR-ABL driven leukemia.
  • 批准号:
    366610
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    Operating Grants
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    $7.29万
  • 财政年份:
    2016
  • 负责人:
    McGlade Catherine J
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Function and regulation of Numb protein isoforms in cancer.
  • 批准号:
    321543
  • 项目类别:
    Operating Grants
  • 资助金额:
    $59.55万
  • 财政年份:
    2015
  • 负责人:
    McGlade Catherine J
  • 依托单位:
Function and regulation of Numb alternative splicing in cancer.
  • 批准号:
    200602
  • 项目类别:
    Operating Grants
  • 资助金额:
    $47.66万
  • 财政年份:
    2010
  • 负责人:
    McGlade Catherine J
  • 依托单位:
海外基金