Functionally characterizing mammalian microRNAs and mRNA interactions controlling cell division.

功能表征哺乳动物 microRNA 和控制细胞分裂的 mRNA 相互作用。

• 批准号: DP1093164
• 负责人: A/Prof Nicole Cloonan
• 金额: $ 29.26万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1093164
• 关键词: Functionally; characterizing; mammalian; microRNAs; mRNA

This project addresses some of the most burning issues in molecular biology and genetic research, and the results will be widely applicable to a broad range of fields, including biotechnology, animal breeding, agricultural production, genetic engineering, medical science, and computational biology. By understanding the regulatory potential of microRNA molecules, we will understand more about species diversity, regulatory networks, and plant and animal development. The early adoption of multi-gigabase next-generation sequencing technology in Australia provides rare and exciting opportunity to lead the world in genome-scale research, and to ensure that Australia has the necessary skill base to remain internationally competitive in this field.

该项目解决了分子生物学和遗传学研究中一些最紧迫的问题，其结果将广泛适用于生物技术、动物育种、农业生产、遗传工程、医学和计算生物学等广泛领域。通过了解microRNA分子的调控潜力，我们将更多地了解物种多样性，调控网络以及动植物发育。在澳大利亚早期采用数十亿次的下一代测序技术提供了罕见和令人兴奋的机会，可以在基因组规模的研究方面领先世界，并确保澳大利亚拥有必要的技能基础，以保持在该领域的国际竞争力。