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Phenotypic analysis of a putative mouse model for 'STING-associated vasculopathy with onset in infancy' (SAVI): an autosomal dominant auto-inflammatory interferonopathy

Phenotypic analysis of a putative mouse model for 'STING-associated vasculopathy with onset in infancy' (SAVI): an autosomal dominant auto-inflammatory interferonopathy
“婴儿期发病的 STING 相关血管病”（SAVI）假定小鼠模型的表型分析：一种常染色体显性自身炎症干扰素病
批准号：
434025
负责人：
Jirik Frank R
金额：
$67.15万
依托单位：
University of Calgary
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
未结题
起止时间：
2020-10-01 至 2025-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=434025&lang=en
关键词：
Acral Vasculopathy And Necrosis Autosomal Dominant Interferonopathy Conditional Gene Activation Via Cre-Loxp Technology Intravital And X-Ray Microscopy Mouse Model Of Human Savi Stimulator Of Interferon Genes (Sting) Sting-Associated Vasculopathy Of

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中文摘要
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英文摘要
'STING-associated vasculopathy with onset in infancy' (SAVI) is a rare, but increasingly recognized, disease of children. Individuals with this condition have been reported in many countries, including Canada. The condition is due to mutations in a gene k
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