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Stimulator of interferon genes (STING)-induced tumour-associated macrophage re-education as a novel strategy for the treatment of lung cancer.

Stimulator of interferon genes (STING)-induced tumour-associated macrophage re-education as a novel strategy for the treatment of lung cancer.
干扰素基因刺激物（STING）诱导肿瘤相关巨噬细胞再教育作为治疗肺癌的新策略。
批准号：
322558
负责人：
Jirik Frank R
金额：
$48.11万
依托单位：
University of Calgary
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-03-01 至 2019-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=322558&lang=en
关键词：
Cyclic Dinucleotides Image Guided Radiation Therapy (Igrt) Imaging Technologies Immunotherapy/Checkpoint Inhibition Non-Small Cell Lung Cancer (Nsclc) Oncolytic Viruses Stimulator Of Interferon Genes (Sting) Syngeneic Models Of Lung Cancer Transge

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英文摘要
'Pre-clinical' modeling of human lung cancers in mice having a functionally-intact immune system is essential to discovering how to best stimulate the immunological killing of cancer cells. We propose an interdisciplinary approach to find novel ways with
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