Investigation into the structure and function of Junctophilin, an important protein in the skeletal and cardiac systems

研究骨骼和心脏系统中的重要蛋白质亲结蛋白的结构和功能

• 批准号: 449783
• 负责人: Yang Zheng Fang
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-12-01 至 2021-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=449783&lang=en
• 关键词: Calcium; Calcium Channels; Cardiac Arrhythmias; Excitation-Contraction Coupling; Junctophilin; Membrane Structure; Muscle Contraction; Mutation; Protein-Protein Interaction

Heartbeats and muscle contractions are essential to life. A small molecule plays a key role in both processes: the calcium ion. Although generally known as a building block for healthy bones, calcium ions are crucial for the function of almost all the cel

心跳和肌肉收缩是生命所必需的。一个小分子在这两个过程中都起着关键作用：钙离子。尽管通常被认为是健康骨骼的组成部分，但钙离子对几乎所有骨骼细胞的功能都是至关重要的。