Novel coding and decoding in suspension arrays for accelerated biomolecular discovery and personalised medicine

悬浮阵列中的新颖编码和解码可加速生物分子发现和个性化医疗

• 批准号: DP1095465
• 负责人: Em/Prof James Piper
• 金额: $ 23.25万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-07-31 至 2013-08-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1095465
• 关键词: Novel; coding; decoding; suspension; arrays

This project will establish an advanced multiplexing technique to rapidly analyse complex biological mixtures, such as cell lysates, food samples or body fluids. It will enable the analysis of not tens, but thousands or more distinctive molecular targets in a single test. This will build the foundations for future generation bioassays, paving the way to emerging personalised medicine. This will lead to new personal diagnostics tools for rapid genotype profiling, to better tailor therapy to the individual patient's specific characteristics. As well as the potential to improve health outcomes, the project will generate significant intellectual property and the opportunity for development of new diagnostic instrumentation in Australia.

该项目将建立一种先进的多路复用技术，以快速分析复杂的生物混合物，如细胞裂解物，食品样品或体液。它将能够在一次测试中分析不是数十个，而是数千个或更多的独特分子目标。这将为下一代生物测定奠定基础，为新兴的个性化医疗铺平道路。这将导致新的个人诊断工具，用于快速基因型分析，以更好地针对个体患者的具体特征进行治疗。除了改善健康结果的潜力外，该项目还将产生重要的知识产权，并为澳大利亚开发新的诊断仪器提供机会。