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A deep phenotyping network for understanding human islet variation in health and diabetes

A deep phenotyping network for understanding human islet variation in health and diabetes
用于了解人类胰岛在健康和糖尿病方面的变异的深层表型网络
批准号:
454361
负责人:
MacDonald Patrick E
金额:
$72.85万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-07-01 至 2026-07-01

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中文摘要
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英文摘要
Insulin is secreted from cells of the pancreatic islets of Langerhans into the blood after a meal to control blood sugar levels. In type 1 diabetes (T1D) islet cells are destroyed by an auto-immune reaction. In type 2 diabetes (T2D), islet cells fail to p
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会议论文
Dysfunctional and Resistant Islet Cell Populations in Human Diabetes
  • 批准号:
    469220
  • 项目类别:
    Operating Grants
  • 资助金额:
    $76.07万
  • 财政年份:
    2022
  • 负责人:
    MacDonald Patrick E
  • 依托单位:
A deep phenotyping network for understanding human islet variation in health and diabetes
  • 批准号:
    446708
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.73万
  • 财政年份:
    2020
  • 负责人:
    MacDonald Patrick E
  • 依托单位:
Canada Research Chairs - Tier 1
  • 批准号:
    424787
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2019
  • 负责人:
    MacDonald Patrick E
  • 依托单位:
Mechanisms controlling the magnitude of insulin secretory responses and their role in type 2 diabetes
  • 批准号:
    344331
  • 项目类别:
    Operating Grants
  • 资助金额:
    $52.91万
  • 财政年份:
    2016
  • 负责人:
    MacDonald Patrick E
  • 依托单位:
海外基金