Assessing the utility of a new class of inheritance mediated by a rare variant genetic risk score for chronic disease prediction

评估由罕见变异遗传风险评分介导的一类新遗传在慢性病预测中的效用

• 批准号: 458558
• 负责人: Lali Ricky
• 金额: $ 7.65万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-11-01 至 2024-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=458558&lang=en
• 关键词: Genetic Risk Scores; Rare Variant Burden Testing; Rare Variants; Whole-Exome Sequencing

Coronary artery disease (CAD) and late-onset Alzheimer's disease (LOAD) are prevalent disorders that collectively encompass the leading cause of morbidity and mortality worldwide while also having a strong genetic basis. Currently, the genetic causes of C

冠状动脉疾病（CAD）和迟发性阿尔茨海默病（LOAD）是普遍存在的疾病，它们共同构成了全球发病率和死亡率的主要原因，同时也具有很强的遗传基础。目前，C的遗传原因