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Investigating genetic interactions between RNA-binding proteins relevant to neurodegenerative disease in C. elegans

Investigating genetic interactions between RNA-binding proteins relevant to neurodegenerative disease in C. elegans
研究与线虫神经退行性疾病相关的 RNA 结合蛋白之间的遗传相互作用
批准号：
466721
负责人：
Premachandran Sharanja
金额：
$1.27万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-12-01 至 2022-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466721&lang=en
关键词：
Als C. Elegans Crispr-Cas9 Disease Gene Expression Genetics Loss-Of-Function Neurodegeneration Post-Transcriptional Gene Regulation Rna-Binding Proteins

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英文摘要
RNA binding proteins (RBPs) are a highly conserved group of post-transcriptional regulators, involved in processes that include mRNA polyadenylation, alternative splicing, nuclear export, and translation. As such, mutated RBPs have emerged as key players
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