Interaction Between Microglia, Amyloid-beta, and Phosphorylated-tau in a Phosphorylated-tau Seeded Alzheimer's Disease Mouse Model.

磷酸化 tau 种子阿尔茨海默病小鼠模型中小胶质细胞、β 淀粉样蛋白和磷酸化 tau 之间的相互作用。

• 批准号: 460557
• 负责人: Lapointe Valrie
• 金额: --
• 依托单位: University of Lethbridge (Alberta)
• 依托单位国家: 加拿大
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-01-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=460557&lang=en
• 关键词: Alzheimer'S Disease; Amyloid; Dementia; Memory; Mouse Model; Phosphorylated Tau

Alzheimer's disease (AD) is a progressive neurodegenerative disease affecting tens of millions of people worldwide, characterized by a gradual loss of memory and other cognitive functions. Two misfolded proteins are of particular importance in the study o

阿尔茨海默病（AD）是一种影响全世界数千万人的进行性神经退行性疾病，其特征在于记忆和其他认知功能的逐渐丧失。两个错误折叠的蛋白质在研究中特别重要，