Depicting disease heterogeneity in neurofibromatosis type 1 and the role of microenvironment in NF1-associated skin tumor formation through personalized tissue-engineered 3D models
Depicting disease heterogeneity in neurofibromatosis type 1 and the role of microenvironment in NF1-associated skin tumor formation through personalized tissue-engineered 3D models
通过个性化组织工程 3D 模型描绘 1 型神经纤维瘤病的疾病异质性以及微环境在 NF1 相关皮肤肿瘤形成中的作用
批准号：
473034
负责人：
Gros-Louis Francois
金额：
$7.29万
依托单位：
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
已结题
起止时间：
2022-09-01 至 2023-09-01
中文摘要
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英文摘要
Neurofibromatosis type 1 (NF1) is an orphan disease causing significant morbidity and mortality. It is a multisystemic genetic disorder especially characterized by cutaneous manifestations that include the development of multiple benign skin tumors, calle
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Depicting disease heterogeneity in neurofibromatosis type 1 and the role of dermal fibroblasts in the establishment of microenvironment favouring NF1-associated skin tumor formation using personalized tissue-engineered 3D models
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批准号：478062
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项目类别：Operating Grants
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资助金额：$81.09万
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财政年份：2023
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负责人：Gros-Louis Francois
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依托单位：
Canada Research Chairs - Tier 1
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批准号：480963
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项目类别：
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资助金额：$101.99万
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财政年份：2022
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负责人：Gros-Louis Francois
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依托单位：
Canada Research Chair - Tier 2
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批准号：378539
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项目类别：
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资助金额：$36.43万
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财政年份：2017
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负责人：Gros-Louis Francois
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依托单位：
Pathogenic Pathways and in-vitro modelization of Intracranial Aneurysms in populations of Inuit and French Canadian descent
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批准号：354692
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项目类别：Operating Grants
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资助金额：$69.38万
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财政年份：2016
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负责人：Gros-Louis Francois
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依托单位：
Tissue-engineered in-vitro skin model to facilitate the identification of disease biomarkers for Amyotrophic Lateral Sclerosis
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批准号：329765
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项目类别：Operating Grants
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资助金额：$7.29万
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财政年份：2015
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负责人：Gros-Louis Francois
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依托单位：
CRC Tier 1
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批准号：284385
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项目类别：
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资助金额：$36.43万
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财政年份：2012
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负责人：Gros-Louis Francois
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依托单位：
海外基金
