New mechanisms regulating the biogenesis of extracellular vesicles
New mechanisms regulating the biogenesis of extracellular vesicles
批准号:
DP240101427
负责人:
Prof Sharad Kumar
金额:
$45.52万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2024
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2024-01-01 至 2026-12-31
中文摘要
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英文摘要
Extracellular vesicles are small packages that contain active components derived from the cell of origin. These vesicles, released by most cell types, are critical for communication between cells. However, the processes of their formation and release remain poorly understood. This project aims to explore how ubiquitination, a type of protein modification system, controls the production of extracellular vesicles. Using a strong collaborative team and highly innovative approaches, the project will generate new knowledge to inform how cells communicate. Expected outcomes include knowledge of broad significance to cell biology, that can be leveraged to develop extracellular vesicles as tools for various biotechnology applications in the future.
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会议论文
Regulation of autophagy dependent cell and tissue deletion
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批准号:DP210100665
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项目类别:Discovery Projects
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资助金额:$35.34万
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财政年份:2021
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负责人:Prof Sharad Kumar
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依托单位:
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依托单位:
Regulation of cell death, cell survival and ubiquitination in normal physiology and disease
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批准号:nhmrc : GNT1103006
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项目类别:Research Fellowships
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资助金额:$85.2万
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财政年份:2016
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负责人:Prof Sharad Kumar
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依托单位:
Regulation of cell death, cell survival and ubiquitination in normal physiology and disease
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批准号:nhmrc : 1103006
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项目类别:Research Fellowships
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资助金额:$58.74万
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财政年份:2016
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负责人:Prof Sharad Kumar
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依托单位:
A novel mechanism for regulating membrane proteins by ubiquitin ligases and their adaptors
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批准号:nhmrc : 1059393
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项目类别:Project Grants
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资助金额:$41.87万
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财政年份:2014
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负责人:Prof Sharad Kumar
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依托单位:
Autophagy and growth signalling in developmentally programmed cell death
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批准号:nhmrc : 1041807
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项目类别:Project Grants
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资助金额:$39.62万
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财政年份:2013
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负责人:Prof Sharad Kumar
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依托单位:
Understanding the role of caspase-2 in cellular stress response and ageing
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批准号:nhmrc : 1021456
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项目类别:Project Grants
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资助金额:$61.25万
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财政年份:2012
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负责人:Prof Sharad Kumar
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依托单位:
Physiological function of Nedd4-2 in regulating the epithelial sodium channel and cystic fibrosis transmembrane conductance regulator
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批准号:nhmrc : 1020755
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项目类别:Project Grants
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资助金额:$63.32万
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财政年份:2012
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负责人:Prof Sharad Kumar
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依托单位:
Regulation of cell death, cell survival and ubiquitination in normal physiology and disease
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批准号:nhmrc : 1002863
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项目类别:Research Fellowships
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资助金额:$54.88万
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财政年份:2011
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负责人:Prof Sharad Kumar
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依托单位:
Characterisation of the tumour suppressor function of caspase-2
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批准号:nhmrc : 626905
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项目类别:NHMRC Project Grants
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资助金额:$40.35万
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财政年份:2010
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负责人:Prof Sharad Kumar
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依托单位:
Regulation of cell death and proliferation by histone demethylases
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批准号:nhmrc : 626903
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项目类别:NHMRC Project Grants
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资助金额:$34.75万
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财政年份:2010
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负责人:Prof Sharad Kumar
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依托单位:
Roles of Ndfip1 and Ndfip2 as adaptors for the Nedd4 family of ubiquitin ligases
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批准号:nhmrc : 508085
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项目类别:NHMRC Project Grants
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资助金额:$43.77万
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财政年份:2008
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负责人:Prof Sharad Kumar
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依托单位:
Caspase-2 function in cell death and disease
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批准号:nhmrc : 453482
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项目类别:NHMRC Project Grants
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资助金额:$35.31万
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财政年份:2007
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负责人:Prof Sharad Kumar
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依托单位:
Caspase function in animal development
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批准号:nhmrc : 399302
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项目类别:NHMRC Project Grants
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资助金额:$45.59万
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财政年份:2006
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负责人:Prof Sharad Kumar
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依托单位:
Research Fellowship - Grant ID:399300
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批准号:nhmrc : 399300
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项目类别:NHMRC Research Fellowships
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资助金额:$50.09万
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财政年份:2006
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负责人:Prof Sharad Kumar
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依托单位:
Temporal and spatial regulation of caspases in development and metamorphosis
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批准号:nhmrc : 250349
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项目类别:NHMRC Project Grants
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资助金额:$31.56万
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财政年份:2003
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负责人:Prof Sharad Kumar
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依托单位:
Characterisation of putative targets of the ubiquitin-protein ligase, Nedd4
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批准号:nhmrc : 157921
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项目类别:NHMRC Project Grants
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资助金额:$17.21万
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财政年份:2001
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负责人:Prof Sharad Kumar
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依托单位:
Molecular regulation of programmed cell death
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批准号:nhmrc : 158068
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项目类别:NHMRC Research Fellowships
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资助金额:$40.47万
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财政年份:2001
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负责人:Prof Sharad Kumar
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依托单位:
Temporal and spatial regulation of caspases in development and metamorphosis
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批准号:nhmrc : 104842
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项目类别:NHMRC Project Grants
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资助金额:$24.61万
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财政年份:2000
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负责人:Prof Sharad Kumar
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依托单位:
Molecular Regulation of Programmed Cell Death
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批准号:nhmrc : 990178
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项目类别:NHMRC Project Grants
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资助金额:$12.83万
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财政年份:1999
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负责人:Prof Sharad Kumar
-
依托单位:
国内基金
海外基金
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