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Hemozoin and Malaria Biomarkers: Role in the modulation of inflammatory responses and development of Malaria-related Pathologies

Hemozoin and Malaria Biomarkers: Role in the modulation of inflammatory responses and development of Malaria-related Pathologies
疟原虫色素和疟疾生物标志物:在调节炎症反应和疟疾相关病理学发展中的作用
批准号:
252607
负责人:
Olivier Martin
金额:
$54.48万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2017-03-01

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英文摘要
In the past, we have been able to clearly demonstrate that the protozoan parasite Leishmania can affect the MO signaling leading to its dysfunctions, thus providing a secure niche where the parasite can divide and progress within its infected host. These
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Cellular and Molecular Mechanisms Underlying Leishmania-Macrophage Interaction: Impact on Cutaneous Leishmaniasis Progression.
Hemozoin: An Inorganic Heme-Based Crystal Responsible for Hepatosplenomegaly Development During Malaria.
Subversion of Macrophage Signaling by the Protozoan Parasite Leishmania
Hemozoin Crystal: A Metabolic Waste Responsible for Inflammatory-Related Pathologies Developed During Malaria Infection.
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