课题基金 / 基金详情

Dissecting the roles of DNA-binding autoinhibition, post-translational modification and protein partnerships in the regulation of the transcription factor ETV6 (or TEL)

Dissecting the roles of DNA-binding autoinhibition, post-translational modification and protein partnerships in the regulation of the transcription factor ETV6 (or TEL)
剖析 DNA 结合自抑制、翻译后修饰和蛋白质伙伴关系在转录因子 ETV6（或 TEL）调节中的作用
批准号：
300387
负责人：
De Soumya
金额：
$6.01万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-11-01 至 2015-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=300387&lang=en
关键词：
Autoinhibition Biomolecular Structure Drug Design Isothermal Titration Calorimetry (Itc) Leukemia Nmr Spectroscopy Protein Dynamics Protein-Dna Interaction Transcription Factors X-Ray Crystallography

项目摘要

项目成果

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Leukemia is a type of cancer that affects blood and bone marrow. The protein ETV6 has been widely implicated in various forms of leukemia and is an important therapeutic target. ETV6 is a transcription factor that plays key roles in the formation of blood
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
海外基金