课题基金 / 基金详情

Molecular pathogenesis of BRCA1-associated and triple-negative breast cancer: mechanism of tissue specificity and identification and characterization of cooperating tumorigenic pathways.

Molecular pathogenesis of BRCA1-associated and triple-negative breast cancer: mechanism of tissue specificity and identification and characterization of cooperating tumorigenic pathways.
BRCA1 相关和三阴性乳腺癌的分子发病机制：组织特异性机制以及协同致瘤途径的识别和表征。
批准号：
194162
负责人：
Cescon David W
金额：
$8.74万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-10-01 至 2013-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=194162&lang=en
关键词：
Animal Models Of Cancer Brca1 Associated Cancer Cancer Medical Oncology Oncogenes And Tumor Suppressor Genes Rnai

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中文摘要
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英文摘要
Breast cancer affects almost 23 000 Canadian women each year, and remains a major cause of death. Five percent all breast cancers, and 80% of inherited cases, are caused by mutations in the BRCA1 gene. Women who carry these mutations are also at high risk
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Discovery and validation of vulnerabilities and therapeutic strategies for cyclin-dependent kinase 4/6 inhibitor-resistant hormone receptor positive breast cancer
  • 批准号：
    435434
  • 项目类别：
    Operating Grants
  • 资助金额：
    $65.2万
  • 财政年份：
    2020
  • 负责人：
    Cescon David W
  • 依托单位：
    University Health Network (Toronto)
Molecular pathogenesis of BRCA1-associated and triple-negative breast cancer: mechanism of tissue specificity and identification and characterization of cooperating tumorigenic pathways.
  • 批准号：
    206486
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $1.46万
  • 财政年份：
    2009
  • 负责人：
    Cescon David W
  • 依托单位：
    University of Toronto