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Effects of tissue plasminogen activator administration on cholinergic and cognitive deficits in in a transgenic model of Alzheimer's disease-like amyloid pathology

Effects of tissue plasminogen activator administration on cholinergic and cognitive deficits in in a transgenic model of Alzheimer's disease-like amyloid pathology
组织纤溶酶原激活剂给药对阿尔茨海默病样淀粉样蛋白病理转基因模型中胆碱能和认知缺陷的影响
批准号：
311872
负责人：
Pentz Rowan D
金额：
$1.27万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-12-01 至 2014-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=311872&lang=en
关键词：
Alzheimer'S Basal Forebrain Cholinergic Nuclei Cholinergic Synapses Fear Conditioning Immunohistochemistry Morris Water Maze Nerve Growth Factor Tissue Plasminogen Activator Transgenic Western Blot

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英文摘要
Alzheimer's disease is the most common form of dementia worldwide and affects over 500 000 Canadians today. Current treatments for Alzheimer's are not very effective. Unless new treatments are found, the number of AD sufferers in Canada is expected to ste
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Immunotherapy against neuroserpin to correct Nerve Growth Factor metabolic dysfunction and consequent cholinergic and cognitive deficits in a transgenic rat model of Alzheimer's disease.
  • 批准号：
    365444
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2016
  • 负责人：
    Pentz Rowan D
  • 依托单位：
    McGill University