Overcoming inactivation of oncolytic reovirus by proteases in breast tumor microenvironments.
Overcoming inactivation of oncolytic reovirus by proteases in breast tumor microenvironments.
批准号:
453388
负责人:
Shmulevitz Maya
金额:
$4.37万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-03-01 至 2023-03-01
中文摘要
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英文摘要
BACKGROUND: Reovirus (T3wt) is in phase 3 clinical trials for treatment of breast and other cancers. My laboratory seeks to further adapt reovirus towards breast tumor cells and environments, with hopes to improve the potency of reovirus therapy. Using ex
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会议论文
Advanced immunotherapeutic oncolytic reovirus combination therapy for breast cancer.
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批准号:450628
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项目类别:Operating Grants
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资助金额:$65.76万
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财政年份:2021
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负责人:Shmulevitz Maya
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依托单位:
Understanding and exploiting post-entry steps of oncolytic reovirus replication and assembly
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批准号:379464
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资助金额:$57.4万
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依托单位:
Multi-mechanistic oncolytic reovirus variants for clearing cancer
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批准号:388214
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项目类别:Operating Grants
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资助金额:$7.27万
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财政年份:2018
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负责人:Shmulevitz Maya
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依托单位:
Canada Research Chair - Tier 2
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批准号:373641
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项目类别:
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资助金额:$36.43万
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财政年份:2016
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负责人:Shmulevitz Maya
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依托单位:
Characterizing structural changes that retarget enteric reovirus towards tumours.
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批准号:266967
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项目类别:Operating Grants
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资助金额:$41.06万
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财政年份:2012
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负责人:Shmulevitz Maya
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依托单位:
CRC Tier 2
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批准号:265793
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项目类别:
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资助金额:$36.43万
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财政年份:2011
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负责人:Shmulevitz Maya
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依托单位: