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Discovering how age-associated increases in pro-inflammatory cytokines contribute to impaired macrophage function & increased susceptibility to disease.

Discovering how age-associated increases in pro-inflammatory cytokines contribute to impaired macrophage function & increased susceptibility to disease.
发现与年龄相关的促炎细胞因子的增加如何导致巨噬细胞功能受损
批准号：
311939
负责人：
Naidoo Aveshni
金额：
$1.27万
依托单位：
McMaster University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-12-01 至 2014-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=311939&lang=en
关键词：
Chronic Inflammation Disease In Elderly Disease Susceptibility Immunosenescence Inflammaging Macrophages Microbial Translocation Myeloid Skewing Pro-Inflammatory Tumor Necrosis Factor Alpha

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中文摘要
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英文摘要
Aging is accompanied by increased levels of protein mediators, known as cytokines, in serum and tissues, and observable changes in immune cell phenotype and function. This “inflammaging” is believed to contribute to a wide spectrum of diseases associated
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Age-associated increases in pro-inflammatory cytokines (e.g. TNF) contribute to impaired macrophage function and increased susceptibility to disease in the elderly.
  • 批准号：
    327778
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2014
  • 负责人：
    Naidoo Aveshni
  • 依托单位：
    McMaster University
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