The Population Biology of Drosophila and Yeasts in Relationship to Their Host Plants

果蝇和酵母与其寄主植物关系的群体生物学

• 批准号: 8700654
• 负责人: William Starmer
• 金额: $ 8万
• 依托单位: Syracuse University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-01-01 至 1989-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8700654&HistoricalAwards=false
• 关键词: Population; Biology; Drosophila; Yeasts; Relationship

Killer yeasts produce extracellular proteins that are toxic to other yeasts. The yeast Pichia kluyveri has several forms that differ in their ability to make killer toxins. The differences are known to be determined by nuclear genes in the natural populations of this yeast. The research described in this proposal will investigate the effects of the genes controlling killer toxin production in P. kluyveri on the ability of this yeast to survive and reproduce. The research is primarily focused on the problem of how genes for production of killer toxins are maintained in natural populations and why some populations contain both killer positive and killer negative strains. This work should add to our understanding of how genetic diversity is maintained in natural communities as well as the role of killer systems in the natural environment. Killer yeasts are also important as contaminants in industry, particularly the brewing industry, so this research may be useful in understanding the killer yeasts that are problems in industrial fermentation.

杀手酵母产生对其他酵母有毒的细胞外蛋白质。毕赤酵母有几种形式，它们制造致命毒素的能力不同。这种差异已知是由这种酵母自然种群中的核基因决定的。本研究将探讨克卢韦氏假单胞菌中控制杀伤毒素产生的基因对这种酵母菌生存和繁殖能力的影响。该研究主要集中在产生杀手毒素的基因如何在自然种群中维持，以及为什么一些种群同时含有杀手阳性和杀手阴性菌株。这项工作应该增加我们对自然群落中遗传多样性是如何维持的理解，以及自然环境中杀手系统的作用。在工业中，特别是在酿造工业中，杀伤酵母也是重要的污染物，因此本研究可能有助于了解工业发酵中存在的杀伤酵母问题。