Clinical application of a novel molecule that expands human cord blood stem cells

扩增人脐带血干细胞的新型分子的临床应用

• 批准号: 306332
• 负责人: Roy Jean
• 金额: $ 73.81万
• 依托单位: CIUSSS Est-de-l'Ile-de- Montral-Maisonneuve Rosemont
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-03-01 至 2017-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=306332&lang=en
• 关键词: Cord Blood Transplantation; Fed Batch Culture System; Hematopoietic Stem Cell Expansion; Novel Agonist Of Stem Cell Renewal; Phase I Clinical Study

Allogeneic hematopoietic stem cell transplantation is a life-saving procedure in patients with blood cancers, but only 25% of transplant candidates have a sibling donor. A matched unrelated donor can be found for 60% of patients but this number is lower f

异基因造血干细胞移植是血癌患者的救命手段，但只有25%的移植候选者有兄弟姐妹捐赠者。60%的患者可以找到匹配的无血缘关系的捐赠者，但这个数字低于