Reptilian Thyroid Physiology

爬行动物甲状腺生理学

• 批准号: 8702490
• 负责人: Henry John-Alder
• 金额: $ 16.55万
• 依托单位: Rutgers University New Brunswick
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-07-15 至 1991-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8702490&HistoricalAwards=false
• 关键词: Reptilian; Thyroid; Physiology

This project proposes to examine the involvement of thyroid hormones in regulating aerobic energetic capacities to sustain locomotor activity in reptiles. As endothermy evolved independently in mammals and birds along essentially parallel lines of reptilian ancestry, these studies on extent reptiles may provide insight into non-thermoregulatory roles of thyroid hormones in the ancestral conditions that led to modern endotherms. Three complementary lines of research will be conducted. Firstly, natural seasonal cycles in total and free levels of thyroid hormones and correlated changes in physiological and behavioral factors will be analyzed to provide the interpretational framework for experimental work. Secondly, laboratory experiments will employ new methods to induce physiological alterations in levels of thyroid hormones in regulating particular processes. Thirdly, field experiments will be done to regulate levels of thyroid hormones in field-active lizards and to test the involvement of seasonal hormone cycles in regulating particular processes. The research is expected to yield new information on the regulation by thyroid hormones of physiological processes that support activity and may help to clarify the adaptive significance of these processes in relation to natural activity.

该项目建议检查甲状腺的参与 激素调节有氧能量能力， 爬行动物的自发活动 随着恒温动物的进化 在哺乳动物和鸟类中独立地沿着沿着基本平行的方向 爬行动物的祖先，这些研究范围爬行动物可能 深入了解甲状腺的非体温调节作用 荷尔蒙在祖先的条件下，导致现代 恒温动物 三条互补的研究路线将是 进行。 第一，自然季节循环的总体和自由 甲状腺激素水平和相关变化 将分析生理和行为因素， 实验工作的解释框架。 第二、 实验室实验将采用新的方法来诱导 甲状腺激素水平的生理变化， 规范特定流程。 第三，田间试验将 甲状腺激素水平的调节， 蜥蜴和测试参与季节性激素周期， 规范特定流程。 这项研究预计将 产生关于甲状腺激素调节的新信息 支持活动的生理过程，可能有助于 阐明这些过程的适应意义， 与自然活动的关系。