Acquisition of an AM 400 Spectrometer

核磁共振光谱（NMR）已成为 有机和生物有机化学的主要分析工具， 在无机和生物物理化学中具有重要意义 也 购置如此精密的仪器 大大提高了一个部门的能力， 前沿研究 二维核磁共振的最新进展（COSEY和NOESY 技术等）极大地增强了它在 这些领域，尽管这样的实验是 非常耗时。 这个奖项，当加上一个 从NIH获得的仪器奖，将使收购 能够进行2-D分析的400 MHz NMR光谱仪 光谱学和其他需要最先进技术的技术 设备和大量的时间。 该仪器还将 补充该部现有的能力， 最大限度地发挥现有设施的整体效用。 程序 从事有机金属化学、有机 合成、生物有机合成和生物有机机理将 通过购买该工具来增强。

Nuclear magnetic resonance spectroscopy (NMR) has become the primary analytical tool in organic and bioorganic chemistry, and of major importance in inorganic and biophysical chemistry as well. Acquisition of such sophisticated instrumentation greatly increases the ability of a department to carry out front line research. Recent advances in two-dimensional (2-D) NMR (COSEY and NOESY techniques, etc.) have dramatically enhanced its application in these fields, in spite of the fact that such experiments are very time-consuming. This award, when coupled with an instrumentation award from NIH, will enable the acquisition of a 400 MHz NMR spectrometer capable of carrying out 2-D spectroscopy and other techniques requiring state-of-the-art equipment and large blocks of time. The instrument will also complement the present capabilities of the department and maximize the overall utility of the present facility. Programs involved in studies of organometallic chemistry, organic synthesis, biorganic synthesis and bioorganic mechanisms will be enhanced by acquisition of the instrument.