Purchase of a High Mass High Resolution Mass Spectrometer

质谱技术，如电子冲击（EI），快速原子轰击（FAB）和场解吸（FD）被用于探测内部结构细节，并获得大量有机，生物有机和有机金属分子的分子组成。获得能够执行这些最先进技术的仪器对于在几个化学领域进行前沿研究是必不可少的。购买高质量高分辨率质谱仪将得到美国国家科学基金会化学共享仪器计划和生物仪器计划的支持，并得到美国国立卫生研究院的奖励。将得到加强的化学领域包括：1)过渡金属烯醇酸酯及相关有机金属化合物的立体选择性合成2)藻胆蛋白的结构分析3)寡核苷酸的结构与功能4)蛋白结合色素的结构测定与研究5)寡核苷酸定向诱变6)过渡金属和热介导的有机转化；7)铁载体配合物的表征；8)有机和有机金属合成中的金属芳烃9)沸石和聚磷酸盐材料模型化合物的合成与表征

Mass spectral techniques such as Electron Impact (EI), Fast Atom Bombardment (FAB) and Field Desorption (FD) are used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The acquisition of instrumentation capable of carrying out these state-of-the-art techniques is essential for the prosecution of frontier research in several fields of chemistry. The purchase of a high mass high resolution mass spectrometer will be facilitated by support from the Chemistry Shared Instrumentation Program and the Biological Instrumentation Program of NSF and by an award from NIH. The areas of chemistry that will be enhanced include: 1) Stereoselective Synthesis of Transition Metal Enolates and Related Organometallic Compounds 2) Structural Analysis of Phycobiliproteins 3) Structure and Function of Oligonucleotides 4) Structural Determination and Studies of Protein-Bound Pigments 5) Oligonucleotide Directed Mutagenisis 6) Transition Metal and Heat-Mediated Organic Transformations 7) Characterization of Siderophore Complexes 8) Metallacaixarenes in Organic and Organometallic Synthesis 9) Synthesis and Characterization of Model Compounds as Zeolite and Polyphosphate Materials